Inter
national
J
our
nal
of
Inf
ormatics
and
Communication
T
echnology
(IJ-ICT)
V
ol.
15,
No.
3,
September
2026,
pp.
1066
∼
1077
ISSN:
2252-8776,
DOI:
10.11591/ijict.v15i3.pp1066-1077
❒
1066
Pr
ognosis
of
v
ector
bor
ne
dengue
disease
outbr
eak
in
urban
ar
eas
using
multi
v
ariate
analysis
Pratik
S.
Machchar
1
,
Pur
vi
N.
Ramanuj
2
,
Rajan
P
atel
3
,
Jitendra
Bhatia
4
,
K
untesh
J
ani
5
1
Gujarat
T
echnological
Uni
v
ersity
,
Ahmedabad,
India
2
V
ishw
akarma
Go
v
ernment
Engineering
Colle
ge,
Ahmedabad,
India
3
Kalol
Institute
of
T
echnology
and
Research
Center
,
India
4
Nirma
Uni
v
ersity
,
Ahmedabad,
India
5
L.D.
Colle
ge
of
Engineering,
Ahmedabad,
India
Article
Inf
o
Article
history:
Recei
v
ed
August
22,
2025
Re
vised
March
14,
2026
Accepted
May
21,
2026
K
eyw
ords:
Deep
learning
Dengue
fe
v
er
Machine
learning
T
ime
series
forecasting
V
ector
-borne
diseases
ABSTRA
CT
V
ector
borne
disease
lik
e
dengue
continues
to
pose
a
signicant
climate-sensiti
v
e
public
health
challenge
in
tropical
re
gions
such
as
Brazil,
Per
u,
and
India.
This
study
e
xamines
the
feasibility
of
predicting
dengue
outbreaks
using
weekly
mul-
ti
v
ariate
time-series
data
from
San
Juan
(SJ),
Puerto
Rico
and
Iquitos
(IQ),
Peru.
Dengue
incidence
w
as
analyzed
alongside
meteorological,
en
vironmental,
and
v
e
getation-based
v
ariables
to
capture
k
e
y
climatic
inuences.
Se
v
eral
machine
learning
and
deep
learning
approaches
were
e
v
aluated,
including
LightGBM.
Model
performance
w
as
assessed
using
root
m
ean
square
error
(RMSE)
and
mean
absolute
error
(MAE).
The
results
sho
w
that
LightGBM
achie
v
ed
the
lo
w-
est
RMSE/MAE,
indicating
strong
short-te
rm
predicti
v
e
accurac
y
and
e
xcellent
interpretability
.
Feature
importance
analysis
and
principal
component
analy-
sis
(PCA)
identied
precipitation,
de
w
point
tempera
ture,
and
humidity
as
the
most
inuential
predictors
of
dengue
incidence.
The
study
demonstrates
that
ad-
v
anced
machine
learning
models
can
serv
e
as
reliable
early
w
arning
systems
for
v
ector
-borne
diseases.
While
this
research
focuses
on
dengue,
the
methodology
is
adaptable
to
other
v
e
ctor
-bone
datasets
and
diseases,
of
fering
a
e
xible
tool
for
public
health
authorities
to
predict
and
mitig
ate
outbreaks
in
di
v
erse
urban
conte
xts.
This
is
an
open
access
article
under
the
CC
BY
-SA
license
.
Corresponding
A
uthor:
Pratik
S.
Machchar
Gujarat
T
echnological
Uni
v
ersity
Ahmedabad,
Gujarat,
India
Email:
pratikmachchar@gmail.com
1.
INTR
ODUCTION
Dengue
fe
v
er
continues
to
pose
a
signicant
and
gro
wing
public
health
threat
in
tropical
and
subtropi-
cal
re
gions
w
orldwide.
T
ransmitted
primarily
by
Aedes
ae
gypti
and
Aedes
albopictus
mosquitoes,
dengue
no
w
places
nearly
half
of
the
global
population
at
risk
of
infection.
In
2024,
the
W
orld
Health
Or
g
anization
(WHO)
reported
o
v
er
14.4
million
dengue
cases
and
more
than
11,200
deaths
across
all
six
WHO
re
gions,
marking
one
of
the
highest
annual
global
b
urdens
on
record
[1].
In
India
,
national
surv
eillance
data
indicate
a
substantial
increase
in
dengue
incidence,
with
o
v
er
233,000
reported
cases
and
nearly
300
associated
deaths
in
2024,
con-
tinuing
a
trend
of
high
disease
b
urden
in
recent
years
[1].
These
gures
reect
the
e
xpanding
geographic
spread
and
climate-sensiti
v
e
dynamics
of
dengue
transmission,
underscoring
its
persistent
public
health
impact.
J
ournal
homepage:
http://ijict.iaescor
e
.com
Evaluation Warning : The document was created with Spire.PDF for Python.
Int
J
Inf
&
Commun
T
echnol
ISSN:
2252-8776
❒
1067
The
four
dengue
serotypes
(DENV1-4)
cause
illness
ranging
from
mild
fe
v
er
to
life-threatening
hem-
orrhagic
complications
[2].
Urbanization
and
climate
change
ha
v
e
e
xpanded
mosquito
habitats.
These
v
ectors
also
transmit
malaria,
Zika,
chikungun
ya,
and
yello
w
fe
v
er
.
En
vironmental
f
actors
lik
e
temperature,
rainf
all,
and
humidity
af
fect
mosquito
breeding
and
virus
replication
[3]-[5].
Higher
temperatures
accelerate
virus
de-
v
elopment,
rainf
all
creates
breeding
sites
[6],
[7],
and
v
e
getation
density
pro
vides
ideal
mosquito
habitats
[8].
Despite
adv
ances
in
s
urv
ei
llance,
predicting
dengue
outbreaks
remains
dif
cult
[9]-[11].
Exis
ting
methods
struggle
to
capture
interactions
between
climate,
human
beha
vior
,
and
mosquito
dynamics
[12],
lim-
iting
timely
public
health
responses
[13]-[15].
This
study
e
v
aluates
multi
v
a
riate
time
series
forecasting
for
dengue
prediction
using
data
from
San
Juan
(SJ)
and
Iquitos
(IQ).
Most
pre
vious
w
ork
focuses
on
uni
v
ariate
statistical/deep
learning
methods,
or
often
with
limited
predictors
[9],
[16],
[17].
In
this
study
,
six
multi
v
ariate
models
—SARIMAX,
LightGBM,
Seq2Seq,
RNN,
CNN-BiLSTM,
and
Stack
ed
LSTM—
comparing
statistical,
machine
learning,
and
deep
learn-
ing
approaches
under
identical
conditions
[11],
[18]-[26].
F
or
each
model,
principal
component
analysis
(PCA)
identies
k
e
y
c
limate
dri
v
ers
of
dengue
i
nci-
dence,
addressing
the
interpretability
g
ap
in
ensemble
methods
[27],
[28].
W
eekly
forecasts
align
with
opera-
tional
surv
eillance
needs,
unlik
e
annual
or
long-term
studies
[18],
[29].
This
w
ork
contrib
utes:
-
An
inte
grated
frame
w
ork
combining
climate
and
epidemiological
v
ariables.
-
Systematic
cross-paradigm
model
e
v
aluation
comparing
classical
statistical
methods
(SARIMAX),
machine
learning
approaches
(LightGBM),
and
deep
learning
architectures
(Seq2Seq,
RNN,
CNN-BiLSTM,
Stack
ed
LSTM)
under
identical
e
xperimental
conditions
to
identify
the
most
ef
fecti
v
e
forecasting
approach
-
Identication
of
inuential
predictors/v
ariables
that
contrib
ute
most
to
dengue
incidence.
-
Comparison
of
weekly
forecast
ability
for
practical
disease
surv
eillance.
The
results
sho
w
that
LightGBM
outperforms
other
approaches,
with
precipitation,
de
w
point
tem-
perature,
and
humidity
identied
as
the
most
inuential
predictors.
While
demonstrated
using
dengue,
the
frame
w
ork
is
broadly
applicable
to
other
v
ector
-borne
diseases
in
urban
settings.
2.
MA
TERIALS
AND
METHODS
2.1.
Dataset
The
dataset
used
for
this
study
focuses
on
v
ector
-borne
disease
predictions,
such
as
dengue,
and
includes
detailed
climate
and
en
vironmental
data
for
tw
o
cities:
SJ
and
IQ
[30]
(Figure
1).
It
spans
se
v
eral
years
on
a
weekly
timescale,
capturing
the
corelation
between
pre
v
ailing
climat
e
v
ariables
and
dengue
outbreaks.
K
e
y
features
include
dengue
case
counts
alongside
v
arious
climate
metrics
such
as
temperature,
precipitation,
and
humidity
,
all
of
which
are
kno
wn
to
inuence
the
transmission
of
v
ector
-
borne
diseases.
2.2.
Data
pr
epr
ocessing
Ef
fecti
v
e
data
preprocessing
is
crucial
for
impro
ving
the
accurac
y
of
models
predicting
v
ector
-borne
disease
outbreaks.
In
this
study
,
multiple
steps
were
tak
en
to
clean
and
prepare
the
dataset
before
applying
forecasting
models.
-
Data
formatting:
The
date
column
w
as
con
v
erted
into
a
standard
DateT
ime
format.
Abnormal
or
erroneous
dates
(e.g.,
1994-02-31)
were
corrected
by
replacing
them
with
corresponding
dates
from
the
pre
vious
year
to
maintain
temporal
consistenc
y
.
-
Handling
missing
and
incorrect
v
alues:
Incorrect
or
f
alse
v
alues,
including
null
v
alues,
were
systematically
identied
and
remo
v
ed
from
the
dataset
to
pre
v
ent
distortion
in
model
predictions.
-
Outlier
detection
and
replacement:
Outliers
were
detect
ed
based
on
statistical
thresholds
and
replaced
with
NaN
v
alues
to
pre
v
ent
sk
e
wed
data
points
from
inuencing
the
analysis.
-
Interpolation
missing
v
alues,
including
those
introduced
by
outlier
replacement,
were
lled
using
interpola-
tion
methods,
ensuring
a
continuous
dataset
without
introducing
bias.
-
Data
scaling:
T
o
standardize
the
dataset
and
a
v
oid
an
y
bias
due
to
dif
fering
v
alue
ranges
across
features,
data
scaling
w
as
applied,
ensuring
uniformity
across
all
v
ariables
for
model
training.
These
preprocessing
steps
were
essential
for
rening
the
dataset,
enabling
accurate
and
reliable
dengue
outbreak
predictions
using
v
arious
forecasting
models.
The
dataset
incorporates
weather
station
data
from
Pr
o
gnosis
of
vector
borne
dengue
disease
outbr
eak
in
urban
ar
eas
using
...
(Pr
aktik
S.
Mac
hc
har)
Evaluation Warning : The document was created with Spire.PDF for Python.
1068
❒
ISSN:
2252-8776
NO
AA,
such
as
maximum,
minimum,
and
a
v
erage
temperatures,
total
precipi
tation,
and
diurnal
temperature
range.
Additionally
,
reanalysis
data
includes
relati
v
e
and
specic
humidity
,
air
temperature,
de
w
point
temper
-
ature,
and
precipitation,
pro
viding
a
comprehensi
v
e
understanding
of
climatic
f
actors.
Satellite-based
precipi-
tation
(PERSIANN)
and
v
e
getation
indices
(ND
VI)
of
fer
further
insights
into
en
vironmental
conditions.
These
features
enable
a
multi
v
ariate
analysis
of
ho
w
f
actors
lik
e
temperature,
rainf
all,
and
humidity
impact
dengue
transmission
dynamics
in
urban
areas.
Figure
1.
Study
locations:
San
Juan
(Puerto
Rico)
and
Iquitos
(Peru)
2.3.
A
v
ailable
parameters
f
or
pr
edicting
dengue
cases
The
dataset
comprises
24
en
vironmental
and
climatic
features
alongside
the
tar
get
v
ariable
(total
dengue
cases),
pro
viding
a
comprehensi
v
e
multi
v
ariate
frame
w
ork
for
outbreak
prediction.
Before
analyz-
ing
the
impact
of
indi
vidual
climate
parameters,
it
is
important
to
understand
ho
w
each
v
ariable
contrib
utes
to
dengue
transmissi
on
.
The
follo
wing
sections
detail
the
main
climate
and
en
vironmental
features
considered
in
this
study
,
starting
with
temperature,
which
plays
a
crucial
role
in
mosquito
de
v
elopment
and
virus
replication.
2.3.1.
T
emperatur
e
-
station
max
temp
c,
station
min
temp
c,
station
a
vg
temp
c:
W
eather
station
data
capturing
daily
tempera-
ture
uctuations,
critical
because
Aedes
mosquitoes
thri
v
e
within
certain
temperature
ranges.
Higher
temper
-
atures
speed
up
mosquito
life
c
ycles
and
virus
replication.
-
reanalysis
max
air
temp
k,
reanalysis
min
air
temp
k,
reanalysis
a
vg
temp
k:
Reanalysis
data
pro
vides
broader
scale
temperature
insights,
important
for
capturing
re
gional
climate
patterns
that
af
fect
mosquito
habitats.
-
reanalysis
tdtr
k,
station
diur
temp
rng
c:
Diurnal
temperature
range
indicates
the
dif
ference
b
e
tween
day
and
night
temperatures.
This
range
af
fects
mosquito
acti
vity
,
biting
beha
vior
,
and
survi
v
al,
directl
y
inuenc-
ing
dengue
transmission
rates.
2.3.2.
Pr
ecipitation
-
station
precip
mm,
precipitation
amt
mm,
reanalysis
precip
amt
kg
per
m2,
reanalysis
sat
precip
amt
mm:
Precipitation
creat
es
breeding
grounds
for
Aedes
mosquitoes,
particularly
in
stagnant
w
ater
.
The
amount
of
rainf
all
inuences
mosquito
population
density
,
while
hea
vy
rains
may
disrupt
breeding
c
ycles
by
w
ashing
a
w
ay
larv
ae.
Monitoring
precipitation
is
essential
for
understanding
v
ector
proliferation
and
disease
risk.
Int
J
Inf
&
Commun
T
echnol,
V
ol.
15,
No.
3,
September
2026:
1066–1077
Evaluation Warning : The document was created with Spire.PDF for Python.
Int
J
Inf
&
Commun
T
echnol
ISSN:
2252-8776
❒
1069
2.3.3.
Humidity
-
reanalysis
relati
v
e
humidity
percent,
reanalysis
specic
humidity
g
per
kg:
Humidity
plays
a
pi
v
otal
role
in
mosquito
survi
v
al
and
longe
vity
.
Higher
humidity
increases
the
lifespan
of
mosquitoes,
allo
wing
them
to
bite
multiple
humans
and
thus
spread
the
disease,
while
relati
v
e
humidity
measures
the
percentage
of
saturation.
-
reanalysis
de
w
point
temp
k:
De
w
point
temperature
reects
moisture
le
v
els
in
the
atmosphere.
Higher
de
w
points
create
f
a
v
orable
conditions
for
mosquito
survi
v
al
and
virus
transmission.
2.3.4.
Diur
nal
temperatur
e
range
-
station
diur
temp
rng
c:
A
smaller
diurnal
temperature
range
indicates
stable
temperatures,
which
f
a
v
or
consistent
mosquito
acti
vity
.
W
ider
ranges
m
ay
disrupt
m
osquito
acti
vity
b
ut
can
also
shorten
the
virus
incubation
period
within
the
v
ector
.
2.3.5.
V
egetation
index
(ND
VI)
-
ndvi
se,
ndvi
sw
,
ndvi
ne,
ndvi
nw:
ND
VI
measures
v
e
getation
density
around
the
city
.
Dense
v
e
getation
pro
vides
ideal
breeding
and
resting
places
for
mosquitoes.
Higher
ND
VI
v
alues
generally
correspond
to
higher
mosquito
populations,
increasing
the
risk
of
v
ector
-borne
disease
transmission
in
those
areas.
Moni-
toring
v
e
getation
helps
identify
hotspots
for
v
ector
acti
vity
.
Each
of
these
parameters
of
fers
unique
insights
into
the
en
vironmental
and
climatic
conditions
con-
ducti
v
e
to
dengue
transmission.
Their
combined
analysis
enables
more
accurate
predictions
of
v
ector
-borne
disease
outbreaks.
2.4.
Principal
component
analysis
Since
the
en
vironmental,
epidemiological,
and
meteorological
features
are
highly
correlated,
PCA
w
as
conducted
to
reduce
dimensionality
,
thereby
impro
ving
model
stability
and
prediction
performance
[8],
[12],
[21].
The
dataset
initially
contained
24
climatic,
en
vironmental
,
and
epidemiological
features.
PCA
w
as
con-
ducted
to
re
du
c
e
dimensionality
and
identify
the
most
informati
v
e
predictors.
As
sho
wn
in
Figure
2,
through
multiple
trials
and
e
xperiments,
four
k
e
y
features
were
nalized:
precipitation
amount
(precipitation
amt
mm),
de
w
point
temperature
(reanalysis
de
w
point
temp
k)
specic
humidity
(reanalysis
specic
humidity
g
per
kg)
and
historical
total
cases
(total
cases).
These
features
consistently
demonstrated
the
strongest
contrib
ution
to
e
xplaining
v
ariance
in
dengue
incidence
patterns.
The
usa
of
these
four
features
across
dif
ferent
models
is
sho
wn
in
Figure
2.
Figure
2.
PCA
analysis
sho
wing
feature
importance
across
all
models
2.5.
Hyper
parameter
tuning
Hyperparameter
tuning
met
hod
s
lik
e
Bayesian
[13]
and
grid
search
[29]
are
popular
methods
for
h
y-
perparameter
optimization.
All
models
were
ne-tuned
using
Optuna
[13].
F
or
each
model,
a
predened
search
space
w
as
e
xplored
o
v
er
multiple
trials,
where
model
performance
w
as
e
v
aluated
using
v
alidation
loss.
The
Pr
o
gnosis
of
vector
borne
dengue
disease
outbr
eak
in
urban
ar
eas
using
...
(Pr
aktik
S.
Mac
hc
har)
Evaluation Warning : The document was created with Spire.PDF for Python.
1070
❒
ISSN:
2252-8776
tuning
process
w
as
carried
out
in
a
consistent
manner
across
models
to
identify
stable
parameter
settings.
The
best-performing
h
yperparameter
congurations
were
then
selected
and
used
for
the
nal
training
and
e
v
aluation
of
each
model.
Details
of
the
optimized
h
yperparameters
for
each
model
are
pro
vided
in
Appendix
A.
3.
RESUL
TS
AND
DISCUSSION
In
this
study
,
multiple
machine
learning
and
deep
learning
models
were
e
v
aluated
to
forecast
dengue
outbreaks
using
multi
v
ariate
time
series
data
from
San
Juan
(sj)
and
Iquitos
(iq).
Six
models
were
tested,
in-
cluding
LightGBM,
Stack
ed
LSTM,
CNN-BiLSTM,
Seq2Seq,
RNN,
SARIMAX
as
sho
wn
in
T
able
1.
The
performance
w
as
assessed
using
root
mean
squared
error
(RMSE)
and
mean
absolute
error
(MAE)
metrics.
RMSE
w
as
selected
as
the
primary
metric
because
it
hea
vily
penalizes
lar
ge
prediction
errors,
which
is
critical
for
dengue
forecasting
where
missing
outbreak
spik
es
has
serious
public
health
consequences.
MAE
comple-
ments
RMSE
by
pro
viding
the
a
v
erage
typical
error
magnitude,
and
together
these
metrics
enable
assessment
of
both
w
orst-case
scenarios
and
consistent
performance—essential
for
epidemiological
forecasting
where
out-
break
timing
and
magnitude
are
paramount.
R²
w
as
e
xcluded
as
it
can
be
misleadingly
high
in
time
series
with
strong
seasonal
patterns
and
does
not
adequately
penalize
temporal
lag
or
phase
shifts
in
outbreak
predictions.
Based
on
comprehensi
v
e
e
v
aluation,
LightGBM
achie
v
ed
the
best
performance
with
an
RMSE
of
16.94
and
MAE
of
11.42.
This
section
presents
an
in-depth
analysis
of
this
model,
while
detailed
results
of
all
other
models
are
pro
vided
in
Appendix
B
for
reference.
T
able
1.
Performance
comparison
of
all
models
Model
RMSE
MAE
LightGBM
16.94
11.42
Stack
ed
LSTM
18.75
18.01
CNN-BiLSTM
22.13
19.38
Seq2Seq
22.23
13.44
RNN
25.27
13.98
SARIMAX
34.90
18.37
3.1.
LightGBM-best
model
The
LightGBM
model
achie
v
ed
the
best
performance
with
an
RMSE
of
16.94
and
MAE
of
11.42,
demonstrating
the
ef
fecti
v
eness
of
gradient
boosting
for
dengue
forecasting.
The
model
sho
wed
strong
predic-
ti
v
e
capability
and
e
xcellent
interpretability
(see
Figure
3).
Figure
3.
Actual
vs
predicted
v
for
LightGBM
model
3.1.1.
Pr
edicti
v
e
perf
ormance
analysis
The
LightGBM
model’
s
predic
tions
demonstrate
strong
alignment
with
actual
outbreak
patterns
using
a
multi
v
ariate
approach
that
inte
grates
four
k
e
y
features:
preci
pitation
amount,
de
w
point
temperature,
total
cases,
and
specic
humidity
.
The
model
e
xcels
at
capturing
o
v
erall
outbreak
trends
with
minimal
noise
in
predictions
and
successfully
predicts
the
magnitude
of
outbreak
peaks
,
though
occasionally
underestimates
Int
J
Inf
&
Commun
T
echnol,
V
ol.
15,
No.
3,
September
2026:
1066–1077
Evaluation Warning : The document was created with Spire.PDF for Python.
Int
J
Inf
&
Commun
T
echnol
ISSN:
2252-8776
❒
1071
e
xtreme
e
v
ents.
The
gradient
boosting
frame
w
ork
with
245
estimat
ors
ef
fecti
v
ely
learns
comple
x
interactions
between
climate
and
epidemiological
v
ariables.
3.1.2.
F
eatur
e
importance
analysis
The
LightGBM
model
w
as
trained
using
four
k
e
y
features
selected
through
feature
selection
and
PC
A:
precipitation
amount
(preci
pitation
amt
mm),
specic
humidity
(reanalysis
specic
humidity
g
per
kg),
de
w
point
temperature
(reanalysis
de
w
point
temp
k),
and
historical
total
cases
(total
cases).
The
model’
s
feature
importance
analysis
re
v
ealed
that
precipitation
emer
ged
as
the
dominant
predictor
among
these
v
ariables,
indi-
cating
that
rainf
all
patterns
create
f
a
v
orable
breeding
conditions
for
mosquito
v
ectors.
De
w
point
temperature
and
specic
humidity
,
both
moisture-related
v
ariables,
signicantly
inuenced
predictions
by
af
fecting
v
ec-
tor
survi
v
al
and
reproduction
rates.
The
tree-based
structure
of
LightGBM
pro
vides
e
xcellent
interpretability
,
allo
wing
the
model
to
capture
non-linear
interactions
between
these
climate
and
epidemiological
v
ariables.
3.2.
Comparati
v
e
analysis
LightGBM,
with
an
RMSE
of
16.94
and
MAE
of
11.42,
pro
vides
e
xcellent
interpretability
and
cap-
tures
comple
x
non-linear
relationships
ef
fecti
v
ely
.
LightGBM
is
suited
for
model
interpretability
and
under
-
standing
of
feature
interactions,
making
it
ideal
for
public
health
applications
where
transparenc
y
in
decision-
making
is
crucial.
3.3.
Principal
component
analysis
and
featur
e
selection
acr
oss
models
PCA
w
as
conducted
to
identify
the
most
inuential
climate
and
en
vironmental
features
for
dengue
pre-
diction.
The
analysis
re
v
ealed
that
three
moisture-related
v
ariables
precipitation
(precipi
tation
amt
mm),
de
w
point
temperature
(reanalysis
de
w
point
temp
k)
and
specic
humidity
(reanalysis
specic
humidity
g
per
kg)
collecti
v
ely
accounted
for
the
majority
of
v
ariance
in
dengue
incidence,
conrming
their
critical
role
in
disease
transmission
dynamics.
Precipitation
emer
ged
as
the
most
frequently
selected
feature,
appearing
in
four
of
six
models
(Light-
GBM,
RNN,
Seq2Seq,
and
SARIMAX),
conrming
its
fundamental
role
in
dengue
prediction.
The
best-
performing
models
utilized
comprehensi
v
e
moisture-related
v
ariables-LightGBM
(RMSE
16.94)
incorporated
precipitation,
de
w
point
tempera
ture,
and
specic
humidity
alongside
historical
case
data.
While
multi
v
ariate
models
generally
outperform
ed
uni
v
ariate
approaches,
Stack
ed
LSTM
(RMSE
18.75)
demonstrated
compet-
iti
v
e
perform
ance
using
only
historical
case
patterns,
indicating
that
temporal
autocorrelation
in
disease
in-
cidence
contains
substantial
predicti
v
e
information.
The
PCA-guided
feature
selection
strate
gy
successfully
identied
inuential
predictors
while
reducing
model
comple
xity
,
pro
viding
strong
e
vidence
for
climate-dri
v
en
dengue
transmission
patterns.
3.4.
Simplicity
vs
complexity
trade-off
The
deep
learning
models,
including
Seq2Seq,
RNN,
CNN-BiLSTM,
and
Stack
ed
LSTM,
pro
vided
moderate
to
good
performance,
with
Stack
ed
LSTM
performing
the
best
among
them.
Ho
we
v
er
,
the
LightGBM
model,
which
is
relati
v
ely
simpler
in
architecture,
outperformed
the
deep
learning
models.
This
outcome
chal-
lenges
the
assum
p
t
ion
that
deeper
,
more
comple
x
architectures
necessarily
yield
better
results
in
multi
v
ariate
time
series
forecasting
tasks.
The
superior
performance
of
traditional
machine
learning
approaches
suggests
that
for
the
gi
v
en
dataset
size
and
feature
space,
model
comple
xity
does
not
al
w
ays
translate
to
impro
v
ed
prediction
accurac
y
.
3.5.
LightGBM’
s
superior
perf
ormance
interpretability
through
its
tree-based
structure
and
gradient
boosting
frame
w
ork.
Its
ability
to
pro
vide
clear
feature
importance
rankings
and
capture
non-linear
interactions
between
climate
v
ariables
mak
es
it
v
aluable
for
understanding
the
dri
v
ers
of
dengue
outbreaks.
Its
transparent
decision-making
process
is
cruc
ial
for
public
health
applications
where
understanding
model
predictions
is
as
important
as
accurac
y
.
The
model’
s
com-
putational
ef
cienc
y
and
strong
predicti
v
e
capability
mak
e
it
ideal
for
operational
forecasting
and
strate
gic
planning.
3.6.
Deep
lear
ning
limitations
The
moderate
performance
of
deep
learning
models
(Stack
ed
LSTM,
CNN-BiLSTM,
Seq2Seq,
and
RNN)
compared
to
LightGBM
highlights
potential
limitations
when
applied
to
this
type
of
dengue
dataset.
Pr
o
gnosis
of
vector
borne
dengue
disease
outbr
eak
in
urban
ar
eas
using
...
(Pr
aktik
S.
Mac
hc
har)
Evaluation Warning : The document was created with Spire.PDF for Python.
1072
❒
ISSN:
2252-8776
While
these
architectures
e
xcel
at
capturing
long-term
dependencies
and
comple
x
temporal
patterns,
the
char
-
acteristics
of
dengue
outbreak
data—including
irre
gular
periodicity
,
sparse
e
xtreme
e
v
ents,
and
climate-disease
interaction
comple
xities—may
pose
challenges
that
traditional
machine
learning
approaches
handle
more
ef-
ciently
.
The
computational
cost
and
relati
v
ely
higher
RMSE
suggest
that
deep
learning
models
need
further
renement
or
additional
training
data
to
compete
with
traditional
approaches
in
this
forecasting
conte
xt.
3.7.
Classical
model
constraints
The
SARIMAX
model’
s
poor
performance
underscores
the
limitations
of
classical
time
series
models
when
applied
to
multi
v
ariate
forecasting
tasks.
SARIMAX’
s
statistical
frame
w
ork,
whi
le
ef
fecti
v
e
for
uni
v
ari-
ate
analysis,
struggles
to
adequately
model
the
comple
x
interactions
between
multiple
climate
v
ariables
that
inuence
dengue
outbreaks.
This
limitation
emphasizes
the
need
for
machine
learning
approaches
that
can
capture
non-linear
relationships
and
feature
interactions
in
epidemiological
forecasting.
The
ndings
ha
v
e
practical
implications
for
dengue
surv
eillance
systems.
The
models
pro
vide
a
cri
ti-
cal
timeframe
for
implementing
pre
v
enti
v
e
interv
entions
and
resource
allocation.
Feature
importance
analysis
consistently
identied
precipi
tation,
de
w
point
temperature,
and
humidity
as
k
e
y
predictors,
which
can
guide
tar
geted
mosquito
control
ef
forts
during
high-risk
climatic
conditions.
LightGBM
is
ideal
for
both
real-time
forecasting
and
strate
gic
planning
decisions
due
to
its
balance
of
accurac
y
and
interpretability
.
Current
limitations
include
the
dataset
being
restricted
to
San
Juan
(SJ)
and
Iquitos
(Iq),
focus
on
climate
v
ariables
without
socioeconomic
f
actors,
and
weekly
resolution
that
may
miss
ner
temporal
dynamics.
Future
research
should
e
xplore
ensemble
approaches
combining
model
s
trengths,
inte
gration
of
additional
data
sources
such
as
satellite
imagery
and
mobi
lity
data,
de
v
elopment
of
city-specic
models,
and
in
v
estig
ation
of
climate
change
scenarios
for
long-term
outbreak
predictions.
Note:
Detailed
r
esults
for
all
other
e
valuated
models
(Seq2Seq,
RNN,
CNN-BiLSTM,
Stac
k
ed
LSTM,
and
SARIMAX)
ar
e
pr
o
vided
in
Appendix
B,
including
performance
metrics,
visualizations,
and
model-specic
analyses.
4.
CONCLUSION
This
research
demonstrates
the
ef
fecti
v
eness
of
using
multi
v
ariate
analysis
and
time
series
forecasting
techniques
for
predicting
outbreaks
of
v
ector
-borne
diseases,
with
a
specic
focus
on
dengue
as
a
demonstra-
tion
case.
The
models
e
xplored
in
this
study
,
including
Seq2Seq,
RNN,
CNN-BiLSTM
,
Stack
ed
LSTM,
and
LightGBM.
Pro
vides
a
di
v
erse
set
of
approaches
for
capturing
the
comple
x
interactions
between
en
vironmental
f
actors
and
disease
transmission.
The
results
highlight
the
potential
of
adv
anced
deep
learning
models,
such
as
Stack
ed
LSTM
and
CNN-BiLSTM,
and
machine
learning
models
lik
e
LightGBM
SARIMAX,
which
strug-
gled
to
handle
the
dataset’
s
comple
xity
.
These
ndings
align
with
recent
comparati
v
e
studies
demonstrating
the
superiority
of
machine
learning
approaches
for
dengue
forecasting.
These
deep
learning
models
were
able
to
model
the
intricate
temporal
and
seasonal
patterns
that
are
critical
in
disease
forecast
ing,
thus
of
fering
more
accurate
predictions.
The
study
reinforces
that
using
a
range
of
models—spanning
from
deep
learning
to
sta-
tistical
approaches—of
fers
a
comprehensi
v
e
me
thod
for
forecasting
v
ector
-borne
disease
outbreaks,
enabling
public
health
authorities
to
deplo
y
proacti
v
e
measures
to
control
the
spread
of
disease
in
urban
areas.
5.
FUTURE
W
ORK
The
future
w
ork
of
this
research
aims
to
enhance
the
model’
s
capabilities
by
e
xploring
more
ad-
v
anced
models
and
comparing
their
perf
ormance
in
predicting
v
ector
-borne
diseases.
Additionally
,
e
xpanding
the
dataset
to
include
di
v
erse
geographical
re
gions
and
other
diseases
lik
e
malaria,
chikungun
ya,
and
Zika
will
allo
w
the
model
to
generalize
better
.
Future
research
may
also
suggest
ne
w
,
impro
v
ed
models
while
incorporat-
ing
additional
v
ariables,
such
as
socio-economic
and
en
vironmental
f
actors.
Furthermore,
inte
grating
real-time
data
streams
could
impro
v
e
prediction
accurac
y
and
assist
in
the
de
v
elopment
of
early
w
arning
systems
for
outbreak
mitig
ation.
Lar
ge
language
models
may
also
be
e
xplored
for
enhanced
forecasting
capabilities.
FUNDING
INFORMA
TION
Authors
state
that
no
funding
w
as
in
v
olv
ed.
Int
J
Inf
&
Commun
T
echnol,
V
ol.
15,
No.
3,
September
2026:
1066–1077
Evaluation Warning : The document was created with Spire.PDF for Python.
Int
J
Inf
&
Commun
T
echnol
ISSN:
2252-8776
❒
1073
A
UTHOR
CONTRIB
UTIONS
ST
A
TEMENT
This
journal
uses
the
Contrib
utor
Roles
T
axonomy
(CRediT)
to
recognize
indi
vidual
author
contrib
u-
tions,
reduce
authorship
disputes,
and
f
acilitate
collaboration.
Name
of
A
uthor
C
M
So
V
a
F
o
I
R
D
O
E
V
i
Su
P
Fu
Pratik
S.
Machchar
✓
✓
✓
✓
✓
✓
✓
✓
✓
✓
✓
✓
Purvi
N.
Ramanuj
✓
✓
Rajan
P
atel
✓
Jitendra
Bhatia
✓
K
untesh
Jani
✓
C
:
C
onceptualization
I
:
I
n
v
estig
ation
V
i
:
V
i
sualization
M
:
M
ethodology
R
:
R
esources
Su
:
Su
pervision
So
:
So
ftw
are
D
:
D
ata
Curation
P
:
P
roject
Administration
V
a
:
V
a
lidation
O
:
Writing
-
O
riginal
Draft
Fu
:
Fu
nding
Acquisition
F
o
:
F
o
rmal
Analysis
E
:
Writing
-
Re
vie
w
&
E
diting
CONFLICT
OF
INTEREST
ST
A
TEMENT
Authors
declare
no
conict
of
interest.
D
A
T
A
A
V
AILABILITY
Deri
v
ed
data
supporting
the
ndings
of
this
study
,
including
dengue
case
records
and
climate
v
aria
bles,
and
the
code
used
for
model
de
v
elopment
is
a
v
ailable
from
the
author
[P
.S.M.]
upon
request.
Some
data
may
be
subject
to
institutional
or
pri
v
ac
y
restrictions.
REFERENCES
[1]
W
orld
Health
Or
g
anization
(WHO),
“Dengue
-
Global
situation,
”
W
eekly
Epidemiological
Record
,
v
ol.
100,
no.
52,
pp.
665–678,
2024,
[Online].
A
v
ailable:
https://www
.who.int/publications/i/item/who-wer10052-665-678.
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APPENDICES
APPENDIX
A.
Model
h
yper
parameters
This
subsection
summarizes
the
main
h
yp
e
rparameters
and
settings
for
each
model
as
used
in
this
study
.
A.1.
LightGBM
Input
features:
[precipitation
amt
mm,
reanalysis
de
w
point
temp
k,
total
cases,
reanalysis
specic
humidity
g
per
kg]
(Multi
v
ariate).
Learning
rate:
0.00475,
L1
re
g:
0.0981,
L2
re
g:
0.0141,
Num
lea
v
es:
245,
Num
estimators:
245,
Feature
fraction:
0.8150,
Max
depth:
8,
Min
data
in
leaf:
74,
RMSE:
16.94.
A.2.
Stack
ed
LSTM
Input
features:
[total
cases]
(Uni
v
ariate),
K
ernel
initializer:
He
normal,
Number
of
layers:
1,
Neurons:
69,
Dropout
rate:
0.105,
Epochs:
97,
Batch
size:
16,
Optim
izer:
Adam,
Acti
v
ation
function:
ReLU,
Early
stopping
patience:
16,
RMSE:
18.75.
A.3.
CNN-BiLSTM
Input
features:
[total
cases]
(Uni
v
ariate),
Number
of
con
v
olutional
lters:
39,
K
ernel
size:
3,
BiLSTM
neurons:
127,
Epochs:
19,
Batch
:
16,
Optimizer:
SGD,
Acti
v
ation:
ELU,
Early
stopping
patience:
11,
RMSE:
22.13.
A.4.
Seq2Seq
Input
features:
[precipitation
amt
mm,
reanalysis
specic
humidity
g
per
kg,
total
cases]
(Multi
v
ari-
ate),
W
indo
w
length:
8,
Neurons:
47,
Dropout
rate:
0.174,
Epochs:
61,
Batch
size:
5,
Optimizer:
Nadam,
Early
stopping
patience:
17,
RMSE:
22.23.
A.5.
RNN
Input
features:
[precipitation
amt
mm,
reanalysis
de
w
point
temp
k,
total
cases,
reanalysis
specic
humidity
g
per
kg]
(Multi
v
ariate).
K
ernel
init:
Glorot
uniform,
W
indo
w
length:
5,
Num
layers:
1,
Neurons:
48,
Dropout:
0.111,
Epochs:
47,
Batch
size:
10,
Optimizer:
RMSprop,
Acti
v
ation:
ReLU,
Early
stopping
patience:
14,
RMSE:
25.27.
Int
J
Inf
&
Commun
T
echnol,
V
ol.
15,
No.
3,
September
2026:
1066–1077
Evaluation Warning : The document was created with Spire.PDF for Python.
Int
J
Inf
&
Commun
T
echnol
ISSN:
2252-8776
❒
1075
A.6.
SARIMAX
Input
(e
xogenous)
features:
[precipitation
amt
mm,
reanalysis
a
vg
temp
k],
T
ar
get
v
ariable:
total
cases,
T
ype:
Multi
v
ariate,
F
orecasting
horizon:
4
steps
ahead,
RMSE:
34.90.
APPENDIX
B.
Detailed
r
esults
of
other
models
This
subsection
pro
vides
comprehensi
v
e
results
for
the
remaining
v
e
models
e
v
aluated
in
the
study:
Seq2Seq,
RNN,
CNN-BiLSTM,
Stack
ed
LSTM,
and
SARIMAX.
B.1.
Seq2Seq
model
The
Seq2Seq
multi
output
model
achie
v
ed
an
RMSE
of
22.23.
This
model’
s
moderate
performance
indicates
its
capability
to
capture
sequential
dependencies,
though
it
did
not
perform
optimally
compared
to
the
best
models.
See
Figure
4
the
Seq2Seq
model
sho
ws
general
alignment
with
observ
ed
outbreaks
b
ut
e
xhibits
signicant
uctuations
during
sharp
changes.
Figure
4.
Actual
vs
predicted
graph
of
Seq2Seq
model
B.2.
RNN
model
The
RNN
multioutput
model
produced
an
RMSE
of
25.27.
The
shallo
w
structure
with
1
layer
and
48
neurons
limited
its
ability
to
fully
capture
the
nuances
of
the
multi
v
ariate
data.
See
Figure
5
the
RNN
model
sho
ws
signi
cant
de
viation
from
actual
data
during
periods
of
rapid
change,
f
ailing
to
predict
higher
peaks
accurately
.
Figure
5.
Actual
vs
predicted
graph
of
RNN
model
B.3.
CNN-BiLSTM
model
The
CNN-BiLSTM
model
achie
v
ed
an
RMSE
of
22.13,
combining
con
v
olutional
layers
for
spatial
feature
e
xtraction
with
bidirectional
LSTMs
for
temporal
dependencies.
See
Figure
6
the
CNN-BiLSTM
sho
ws
reasonable
alignment
with
actual
data
though
struggles
with
certain
peaks.
Pr
o
gnosis
of
vector
borne
dengue
disease
outbr
eak
in
urban
ar
eas
using
...
(Pr
aktik
S.
Mac
hc
har)
Evaluation Warning : The document was created with Spire.PDF for Python.